Escalation of commitment causes people to continue a failing course of action. We study the role of construal level in such escalation of commitment. Consistent with the widely held view of construal level as a primed effect, we employed a commonly used prime for manipulating this construct in a laboratory experiment. Our findings revealed that the prime failed to produce statistically significant differences in construal level, which was measured using the Behavior Identification Form. Furthermore, there was no effect of the (...) prime on escalation of commitment, or on constructs that have previously been linked to construal level such as the perceived importance of feasibility considerations relative to desirability considerations, and the number of pros and cons that subjects can think of.Interestingly, however, subjects’ actual construal level scores on the BIF were found to significantly affect escalation. Specifically, our findings show that people with a low construal level are less willing to continue a failing project. This relation is mediated by the perceived importance of the feasibility of the project relative to its desirability. For people with a low construal level, the perceived importance of feasibility relative to desirability is higher, which in turn makes escalation of commitment less likely.Our findings are consistent with prior research suggesting that priming construal level may not always be effective. Thus, while construal level has typically been regarded as a state-like variable that can be primed, in this study, we show that construal level may also be considered as a trait. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Executive functions (EFs) and impulsivity are dimensions of self-regulation that are both related to psychopathology. However, self-report measures of impulsivity and laboratory EF tasks typically display small correlations, and existing research indicates that impulsivity and EFs may tap separate aspects of self-regulation that independently statistically predict psychopathology in adulthood. However, relationships between EFs, impulsivity, and psychopathology may be different in childhood compared to adulthood. Here, we examine whether these patterns hold in the baseline assessment of the Adolescent Brain and Cognitive (...) Development (ABCD) sample, a national sample of over 11,000 children (including 749 twin pairs) ages 9–10 years. We examine the phenotypic and genetic relationships among latent variables for different components of EFs and multiple facets of impulsivity. Additionally, we assess how EFs and impulsivity relate to composite measures and latent variables of psychopathology derived from parent report. EFs were weakly correlated with impulsivity, and the strength varied by impulsivity facet, emphasizing their separability. We did not identify significant genetic and environmental correlations between EFs and impulsivity. Moreover, controlling for their small relationships with each other, both EFs and some facets of impulsivity statistically predicted an Externalizing factor, attention problems, and social problems, and twin analyses suggested these relationships were genetic in origin. These findings indicate that EFs and impulsivity represent phenotypically and genetically separable aspects of self-regulation that are both transdiagnostic correlates of psychopathology in childhood. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 22 (2002) 127-131 [Access article in PDF] Beyond the Usual Alternatives in Buddhist-Christian Dialogue: A Trinitarian Pluralist Approach Harry L. Wells Humboldt State University When I was first asked to present this paper, I was concerned about the assignment —"Beyond the Usual Alternatives." I was told that the usual alternatives were exclusivism, inclusivism, and pluralism. I consider myself a pluralist, so how was I to go beyond (...) what I thought was the best paradigm? But I must make clear that I am a pluralist in the camp of Raimundo Panikkar and not of John Hick, the latter's approach being one that Panikkar has clearly "gone beyond" in my estimation. While pondering the dilemma of how to approach this paper, I auspiciously reencountered the breathtaking profundity of early Christian writings on the nature of reality as Trinitarian. What I found there was an incredibly dynamic notion of reality that refuses to be reductionistic to dualistic modes of analysis. I will do two main things in this paper: I will discuss the Christian experience and understanding of "the mystery of the Living God," including the Trinity and the Christ. In doing this, I will draw upon the book The Roots of Christian Mysticism, by Olivier Clement (New York: New City Press, 1993), whose exposition of these things has been one of rare clarity and wisdom. I will then reflect upon how the Christian Trinitarian reality can serve as a Christian framework for understanding pluralism and interreligious dialogue. If these reflections manage to move us beyond our usual alternatives, it is because they capture a profundity that early Christians knew was eternal and among us. The Mystery of the Living God God is always hidden and universal. That is the mystery of the Living God. Because all things spring forth from God, the world both hides and reveals God's being. God's being is expressed in particular relations that both reveal and conceal; God's being can never be objectified, though it is the horizon in which all things are situated. That is why we can only speak of the living God, as an encounter with God. As Clement points out: "The inexhaustible nature of transcendence is expressed in the profusion of creatures. The universe is the first Bible. Each being manifests the creative word [End Page 127] [the Logos of God] which gives it its identity and attracts it. Each being manifests a dynamic idea, something willed by God. Ultimately each thing is a created name of him who cannot be named" (Clement, p. 27).But to say "willed by God" in a Christian context does not mean a closed monotheism, with a notion of Supreme Being existing objectively independent of the creation. In its very heart, Christianity says God is inexhaustible communion.Dionysius the Areopagite, a pseudonym of an early-fifth-century Christian writer, wrote a treatise called "Divine Names." In it, he speaks of how from all eternity, God lives and reigns in glory, with each ray of glory being a divine Name, and these Names are innumerable. Early Christian writers spoke of these as the powers or energies that spring forth from the unapproachable nature of God that give each created reality, or each emerging manifestation, both its density and transparency. In other words, all things spring forth within God and are modes of the divine presence, receiving its density or particular identity, while clearly being transparent, arising in God. Each creature, each entity names in its own peculiar fashion the divine Names. To say, "from all eternity, God lives and reigns in glory" is to recognize that the very inexhaustible communion that is the cosmos arises from all eternity in the very nature of God. As Gregory Nazianzen proclaims in his work "Dogmatic Poems":... Everything that exists prays to thee And to thee every creature that can read thy universe Sends up a hymn of silence. In thee alone all things dwell. With a single impulse all things find their goal in thee. Thou art the purpose of every creature. Thou art... (shrink)

Professor Plant has presented a briefer treatment of Hegel’s philosophical development than did H. S. Harris in Towards the Sunlight, and a considerably more historical, epistemological and metaphysical treatment than is presented in Pelcynski’s Hegel; Political Philosophy and not so exhaustive an account of the political and social philosophy as appears in Avineri’s Hegel’s Philosophy of the Modern State. These four books taken together testify to the importance of Hegel on the contemporary philosophic scene. Plant’s volume is perhaps the (...) best in that it pulls together the various philosophical, political, and social strains in brief compass, for he demonstrates quite convincingly, as did Avineri and Harris, that the political and metaphysical writings of Hegel are closely interconnected and that the interpretation of art and religion flow from his considered interpretation of his contemporary cultural situation. Plant, with Marx, Engels, Kierkegaard, Baur, Feuerbach et al. and against Findlay and Bergman, argues that there is a Christian theological residue in Hegel’s system, but surprisingly, the fruit of the system is clarification not mystification. Only with that residue is the system and totality really explicable. An altogether welcome book.—R.L.P. (shrink)

In this stimulating book, six leading philosophers--Karl-Otto Apel, Robert Brandom, Karsten Harries, Martha Nussbaum, Barry Stroud, and Allen Wood--consider the nature of philosophy. Although each of them has a unique perspective, they all seem to agree that philosophy seeks to uncover hidden assumptions and concepts in order to expose them to critical scrutiny. It is thus entirely fitting that philosophers should examine their own assumptions about the nature of their discipline. As they delve into the nature of philosophy, the authors (...) address many fascinating subjects: what makes philosophy different from natural science, religion, and other branches of the humanities; whether philosophy can contribute to political transformation, and if so, how; whether there can ever be an "end of philosophy"; and more. The editors' introduction ties together the contributors' diverse perspectives by noting common themes, similarities, and differences. (shrink)

Leibniz's predicate-in-notion principle and some of its alleged consequences, by C. D. Broad.--On Leibniz's metaphysics, by L. Couturat.--Philosophical reflections of Leibniz on law, politics, and the state, by C. J. Friedrich.--The root of contingency, by E. M. Curley.--Monadology, by M. Furth.--Individual substance, by I. Hacking.--Leibniz on plenitude, relations, and the "reign of the law," by J. Hintikka.--Leibniz's theory of the ideality of relations, by H. Ishiguro.--Leibniz and Spinoza on activity, by M. Kneale.--Leibniz and Newton, by A. Koyré.--Plenitude and sufficient reason (...) in Leibniz and Spinoza, by A. O. Lovejoy.--Leibniz on possible worlds, by B. Mates.--Recent work on the philosophy of Leibniz, by B. Russell.--On Leibniz's explication of "necessary truth," by M. D. Wilson.--Bibliography (p. [421]-425). (shrink)

Two dogmas of empiricism, by W. V. Quine.--In defense of a dogma, by H. P. Grice and P. F. Strawson.--The analytic and the synthetic: an untenable dualism, by M. G. White.--Synonymity, by B. Mates.--The meaning of a word, by J. L. Austin.--Meaning and synonymy in natural languages, by R. Carnap.--Analytic-synthetic, by J. Bennett.--On "analytic," by R. M. Martin.--Selected bibliography (p. [188]-196).

Bering's argument that human beings are endowed with a cognitive system dedicated to forming illusory representations of psychological immortality relies on the claim that children's beliefs in the afterlife are not the result of religious teaching. We suggest four reasons why this claim is unsatisfactory.

A special issue of _The Philosophical Forum_, one of the most prestigious philosophy journals, is now available to a wider readership through its publication in book form. The volume includes twelve essays in three sections-- Philosophical Traditions; the African-American Tradition; and Racism, Identity, and Social Life. Contributors are: K. Anthony Appiah, Kwasi Wiredu, Lucius Outlaw, Leonard Harris, Bernard Boxill, Frank M. Kirkland, Tommy L. Lott, Adrian M.S. Piper, Laurence Thomas, Michele M. Moody-Adams, Anita L. Allen, and Howard McGary. The (...) introduction is by John P. Pittman. (shrink)

Social media applications such as Twitter, YouTube and Facebook have attained huge popularity, with more than three billion people and organizations predicted to have a social networking account by 2015. Social media offers a rapid avenue of communication with the public and has potential benefits for communicable disease control and surveillance. However, its application in everyday public health practice raises a number of important issues around confidentiality and autonomy. We report here a case from local level health protection where the (...) friend of an individual with meningococcal septicaemia used a social networking site to notify potential contacts. (shrink)

Spanish influence in the New World was particularly acute in the areas of medicine and medical education. From the time of Columbus forward prominent medical experts journeyed to Latin America establishing medical schools and research centers. This essay chronicles the history of Latin America with a strong focus on the physicians and scientists who brought modern scientific medicine, as it wag then known in Western Europe, to the Americas.

Despite recent research showing that children rapidly interpret human action in terms of intention, a long tradition of empirical research on moral development and recent conceptual analyses of the deontic domain suggest that children do not apply their understanding of intention to the deontic domain. However, two experiments are described showing that children do make that connection. Preschool children heard stories in which a protagonist was obliged to meet a particular condition if an action was to be taken (e.g. obliged (...) to wear a coat if playing outside). When shown four pictures depicting each possible combination of: (1) the protagonist either performing the action or not, and (2) deliberately or accidentally failing to meet the obligation, children appropriately identified the protagonist as naughty when he or she was depicted as deliberately not meeting the obligation while performing the action. The findings proved to be robust across two different cultural settings. Implications for research on children’s developing theory of mind and their understanding of deontic concepts are discussed. (shrink)

In all domains of life, transmembrane proteins from the ATP‐binding cassette (ABC) transporter family drive the translocation of diverse substances across lipid bilayers. In pathogenic fungi, the ABC transporters of the pleiotropic drug resistance (PDR) subfamily confer antibiotic resistance and so are of interest as therapeutic targets. They also drive the quest for understanding how ABC transporters can generally accommodate such a wide range of substrates. The Pdr5 transporter from baker's yeast is representative of the PDR group and, ever since (...) its discovery more than 30 years ago, has been the subject of extensive functional analyses. A new perspective of these studies has been recently provided in the framework of the first electron cryo‐microscopy structures of Pdr5, as well as emergent applications of machine learning in the field. Taken together, the old and the new developments have been used to propose a mechanism for the transport process in PDR proteins. This mechanism involves a “flippase” step that moves the substrates from one leaflet of the bilayer to the other, as a central element of cellular efflux. (shrink)

The article is a critique of malcolm and the wittgensteinians and their criticisms of russell which the author finds to be "prosecuting russell on false charges." (staff).